In some cases, pancreatitis is linked to inherited abnormalities of the pancreas, most commonly cystic fibrosis. Genetic testing can be a useful in detecting patients susceptible to hereditary pancreatitis.

Like chronic pancreatitis, hereditary pancreatitis is a progressive disease that can likely cause permanent problems. Patients could experience chronic pain, diarrhea, malnutrition, or diabetes. Treatment focuses on pain control and pancreatic enzyme replacement.